GenetixBayEST. 2009
Glossary · Pests and diseases

Hop latent viroid

HLVd, a small infectious RNA that spreads through sap and tools, causing stunting, brittle stems, small loose buds and reduced resin in cannabis; called dudding.

Also written HLVdhop latent viroid diseaseduddingdudding diseasedudsdudded plants

EstablishedDraft: awaiting expert reviewUpdated

Hop latent viroid (HLVd) is a viroid, a tiny circular RNA of about 256 nucleotides with no protein coat, that infects hops and cannabis. In cannabis it causes "dudding": plants that grow slowly, with shorter internodes, brittle stems, smaller and looser flowers, and less resin. Many infected plants show few or no symptoms for long periods, especially mothers in veg, which is how it spreads unnoticed.

In practice

HLVd moves in sap: on scissors, razors, hands and clones taken from infected mothers. It is also found in roots and recirculating solution, and seed transmission has been reported at low ratesbeing reviewed. Detection needs a lab test, typically RT-qPCR on root or leaf tissue. There is no cure for an infected plant. Clean-up relies on testing mothers, discarding positives, sterilising tools between plants, and recovering clean stock by meristem tip culture.

Myth check

"Clone decline" or "genetic drift" in old cuts is a pathogen story, not a genetics story. GenetixBay's house position is that there is zero genetic drift in kept cuts apart from pathogens such as HLVd; the founder keeps cuts more than 40 years old with no decline. Label: Supported. See HLVd and viruses and Mythbusters.

Don't confuse with

Related terms

Sources

  1. Adkar-Purushothama CR, Sano T, Perreault J-P, 2023. Hop latent viroid: a hidden threat to the cannabis industry. Viruses 15(3):681. ncbi.nlm.nih.gov/pmc/articles/PMC10053334/
  2. Punja ZK et al., 2025. Hop latent viroid transmission, spread and longevity in cannabis; meristem tip culture. Plants 14(5):830. mdpi.com/2223-7747/14/5/830
  3. Oregon State University Extension. Hop latent viroid in hemp (EM 9570). extension.oregonstate.edu/catalog/em-9570-hop-latent-viroid-
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