GenetixBayEST. 2009
Glossary · Cannabinoids and terpenes

THC

THC (Δ9-tetrahydrocannabinol) is the neutral, decarboxylated cannabinoid mainly responsible for cannabis's reported intoxicating effects; the living plant makes it almost entirely as THCA.

Also written delta-9-THCΔ9-THCd9delta 9tetrahydrocannabinoldelta-9-tetrahydrocannabinol

EstablishedDraft: awaiting expert reviewUpdated

THC, strictly Δ9-tetrahydrocannabinol, is the neutral cannabinoid that acts on CB1 receptors and is associated with the reported intoxicating effects of cannabis. The plant makes very little of it directly. It makes THCA, which loses a carboxyl group (decarboxylation) with heat and time to become THC. With further oxidation, THC slowly degrades to CBN.

In practice

On a COA for dried flower, Δ9-THC itself is usually a small number, often under 1-2% w/w, while THCA might read 18-25%. The figure on a retail label is normally "total THC", which combines both. When someone says "this plant is 22% THC", they nearly always mean total THC, not the Δ9-THC line.

Units and formula

Reported as % w/w (or mg/g; 1% = 10 mg/g). Total THC = Δ9-THC + 0.877 × THCA.

Don't confuse with

  • THCA: the acid form the plant actually makes; not intoxicating until decarboxylated.
  • Delta-8 THC: an isomer present only in traces in the plant; commercial delta-8 is converted from CBD.
  • Total THC: a calculated figure, not a single measured compound.

Related terms

Sources

  1. ElSohly MA, Slade D. 2005. Chemical constituents of marijuana: the complex mixture of natural cannabinoids. Life Sciences 78(5):539-548..
  2. Wang M, Wang YH, Avula B, et al. 2016. Decarboxylation study of acidic cannabinoids: a novel approach using ultra-high-performance supercritical fluid chromatography/photodiode array-mass spectrometry. Cannabis and Cannabinoid Research 1(1):262-271..
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