GenetixBayEST. 2009
Glossary · Cannabinoids and terpenes

CBD

CBD (cannabidiol) is a non-intoxicating neutral cannabinoid formed when CBDA decarboxylates; hemp-type and CBD-dominant cannabis make it mainly as CBDA in their trichomes.

Also written cannabidiolC.B.D.neutral CBD

EstablishedDraft: awaiting expert reviewUpdated

CBD, cannabidiol, is the neutral cannabinoid formed when CBDA loses its carboxyl group. It does not produce the intoxication associated with THC. Like THC, it barely exists in the living plant; the plant makes CBDA through the enzyme CBDA synthase, and the conversion to CBD happens with heat and time.

In practice

Growers classify plants by their THC:CBD balance: THC-dominant, balanced (roughly 1:1) or CBD-dominant. A CBD-dominant flower COA might show CBDA at 12% w/w, CBD at 0.5% w/w and total THC under 0.5% w/w. That ratio is set mainly by genetics at the synthase locus, so it is fixed for a given plant and reliable across clones.

GenetixBay makes no health or therapeutic claims about CBD. Effects are reported, not promised.

Units and formula

Total CBD = CBD + 0.877 × CBDA, in % w/w.

Don't confuse with

  • CBDA: the acid form the plant actually makes.
  • CBN: an oxidation product of THC, not related to CBD despite the similar name.
  • Hemp: a legal category based on THC, not a chemical definition of "CBD plant".

Related terms

Sources

  1. Taura F, Sirikantaramas S, Shoyama Y, et al. 2007. Cannabidiolic-acid synthase, the chemotype-determining enzyme in the fiber-type Cannabis sativa. FEBS Letters 581(16):2929-2934..
  2. Hanuš LO, Meyer SM, Muñoz E, Taglialatela-Scafati O, Appendino G. 2016. Phytocannabinoids: a unified critical inventory. Natural Product Reports 33(12):1357-1392..
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