GenetixBayEST. 2009
Glossary · Genetics and breeding

Locus

A locus is the fixed position on a chromosome where a particular gene or DNA marker sits; the plural is loci.

Also written locigene locusgenetic locus

EstablishedDraft: awaiting expert reviewUpdated

A locus is the fixed physical position on a chromosome where a gene or a DNA marker sits. The plural is loci. Every plant of the species has the same loci in the same order (barring rearrangements); what differs between plants is which alleles occupy them.

In practice

Breeders talk about loci when one position controls a clear trait. The cannabinoid synthase region is often called the B locus, after de Meijer's model of THC/CBD inheritance. Autoflowering behaviour maps to a major locus named Autoflower1 (Toth et al. 2022). DNA tests report results locus by locus: a genotyping panel might read a few thousand SNP loci and compare them between two cuts.

When a trait is controlled by many loci of small effect, the regions are called quantitative trait loci (QTL). Most yield and vigour traits fall in that group.

Don't confuse with

  • Gene: a gene occupies a locus, but a locus can also be a marker with no known function.
  • Allele: the variant found at the locus.
  • Chromosome: the whole DNA molecule that carries thousands of loci. Cannabis has 10 chromosome pairs.

Related terms

Sources

  1. de Meijer EPM, Bagatta M, Carboni A, et al. 2003. The inheritance of chemical phenotype in Cannabis sativa L. Genetics 163(1):335-346. doi.org/10.1093/genetics/163.1.335
  2. Toth JA, Stack GM, Carlson CH, Smart LB. 2022. Identification and mapping of major-effect flowering time loci Autoflower1 and Early1 in Cannabis sativa L. Frontiers in Plant Science 13:991680. doi.org/10.3389/fpls.2022.991680
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