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Glossary · Cannabinoids and terpenes

Terpenoid

A terpenoid is a terpene-derived compound that carries extra functional groups, usually oxygen (alcohols, oxides, ketones), such as linalool, bisabolol or caryophyllene oxide.

Also written terpenoidsisoprenoidisoprenoidsoxygenated terpene

EstablishedDraft: awaiting expert reviewUpdated

A terpenoid, also called an isoprenoid, is a compound built from isoprene units like a terpene but modified, typically with oxygen. Linalool and geraniol (alcohols), eucalyptol and caryophyllene oxide (ethers/oxides) and bisabolol are all terpenoids. In chemistry "terpene" is the plain hydrocarbon and "terpenoid" the modified form; in cannabis talk the two words are used interchangeably.

In practice

Lab terpene panels list both kinds together. Oxygenated terpenoids are generally less volatile than the hydrocarbon monoterpenes, so they tend to survive drying and storage better; some, like caryophyllene oxide, actually increase as their parent compound oxidises. Cannabinoids are, strictly, meroterpenoids: part terpene, part polyketide. That is the sense in which the cannabinoid and terpene pathways are related.

Don't confuse with

  • Terpene: the hydrocarbon parent class.
  • Flavonoid: a separate class of phenolic compounds.
  • Terpene profile: the measured mix in a sample, not a chemical class.

Related terms

Sources

  1. Booth JK, Bohlmann J. 2019. Terpenes in Cannabis sativa: from plant genome to humans. Plant Science 284:67-72..
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