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Glossary · Genetics and breeding

Heterozygous

A plant is heterozygous at a locus when it carries two different alleles there (Aa), so its offspring can inherit either one and segregate.

Also written heterozygoteheterozygosityheterozygoteshet

EstablishedDraft: awaiting expert reviewUpdated

A plant is heterozygous at a locus when its two alleles differ, for example Aa. Half its gametes carry A and half carry a. When heterozygous plants are crossed or selfed, their offspring segregate into different genotypes, which is why seed from a heterozygous plant varies.

In practice

Most cannabis cultivars on the market are highly heterozygous: they are hybrids of hybrids. That is why a seed pack from two famous parents throws a spread of plants and why an elite clone's seed rarely reproduces the clone. The clone holds its heterozygous combination intact only because it is propagated vegetatively.

"Het" is breeder shorthand for a plant known to carry one copy of a recessive allele, as in "het for the auto trait". A test cross or a DNA marker can confirm it.

Heterozygosity is not a defect. High heterozygosity in F1 hybrids is associated with hybrid vigour, and wild or landrace populations keep plenty of it.

Don't confuse with

  • Homozygous: two identical alleles.
  • Hybrid: a cross between different parents; hybrids are usually heterozygous at many loci, but a hybrid between two different inbred lines is uniform even so.
  • Unstable: heterozygous plants are genetically normal; "unstable" in breeder talk means the seed line does not breed true.

Related terms

Sources

  1. Allard RW. 1999. Principles of Plant Breeding, 2nd edition. John Wiley & Sons, New York. ISBN 978-0-471-02309-0.
  2. Acquaah G. 2012. Principles of Plant Genetics and Breeding, 2nd edition. Wiley-Blackwell. doi.org/10.1002/9781118313718
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