GenetixBayEST. 2009
Nutrients · Intermediate · 4 min read

Magnesium (Mg) in cannabis: interveinal yellowing, targets and the K-Ca competition

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

Supported
Draft: awaiting expert review Updated
VegFlowerAny system

Being reviewed. Our editors are double-checking a few figures in this article against primary sources. Marked passages may change.

Short answer. Magnesium is the atom at the centre of every chlorophyll molecule. A cannabis dose-response trial found about 35–70 mg/L Mg optimal in veg [1], and a follow-up found Mg supply increased cannabinoid and terpene production in flower [2]. Deficiency shows as yellowing between the veins of older leaves while the veins stay green [3]. It is often induced by low pH or by too much potassium, calcium or ammonium, so check those before adding more Mg.

What's happening

Mg²⁺ is part of chlorophyll, activates enzymes including Rubisco and ATPases, and is needed to load sugars into the phloem [7]. It is mobile, so the plant pulls it from old leaves to supply new ones; symptoms begin low on the plant.

Mg uptake is weak compared with K⁺ and Ca²⁺. When K or Ca is high, or NH₄⁺ is a large share of N, Mg uptake drops. In cannabis, rising K supply was linked to lower Ca and Mg uptake [6]. That is why a PK booster or heavy Cal(cium)-only supplement can produce a Mg deficiency.

Mg demand also varies by cultivar: genotypes on the same feed take up and move nutrients differently [6]. Together with RO water, coco's cation exchange and root-zone pH, that explains most "Mg-hungry" plants. "LEDs need more Cal-Mag" is a Myth: the light source doesn't raise Mg demand. See Cal-Mag.

How to recognise it

  • Early: faint interveinal yellowing on lower, older leaves [3].
  • Progressing: stronger contrast; veins stay green while the tissue between them goes yellow [3].
  • Advanced: stark green-vein, yellow-blade pattern with necrotic patches [3]. In DWC flower, symptoms began in week 4 on lower fan leaves and later spread to younger leaves by weeks 5–6, with midribs and margins staying green; inflorescence fresh weight was about 33% lower [4].
  • Differential: iron and manganese also cause interveinal chlorosis, but on new growth. K deficiency starts at margins, not between veins. Late-flower senescence is general fading, not a crisp vein pattern.

Numbers that matter

Parameter Target Conditions / notes
Solution Mg, seedlings/clones 25–40 mg/L Grower practice
Solution Mg, veg 35–70 mg/L Optimum in a cannabis trial [1]
Solution Mg, flower 40–70 mg/L Mg raised cannabinoids and terpenes; the study spanned 2–140 mg/L [2].being reviewed
Ca:Mg ratio (mass) ~3:1 to 4:1 Grower practice; standard Hoagland is 200:49 ≈ 4:1
Leaf Mg, healthy (most recent mature leaf) 0.30–0.65% dry weight NC State floral hemp [5]
Leaf Mg at first deficiency symptoms ~0.12% Cannabis, sand culture [3]

What to check first

  1. pH. Soilless below about 5.5 or soil below about 6.0 reduces Mg availability. Keep soilless at 5.5–6.5 and soil at 6.0–7.0 (accepted practice; see pH and nutrient availability).
  2. K and Ca levels. Did you add a PK booster or extra calcium recently?
  3. Water. RO water supplies no Mg. Hard water often supplies 10–40 mg/L.
  4. Coco. Unbuffered coco can bind Mg (see buffering coco).
  5. Roots. Cold or waterlogged roots absorb poorly.

How to fix it

  • Mineral: magnesium sulfate heptahydrate (Epsom salt, ≈9.9% Mg, 13% S). 0.5 g/L supplies about 50 mg/L Mg and 65 mg/L S. Magnesium nitrate (≈9.5% Mg, 11% N) if you also want N.
  • Foliar (veg): Epsom salt at about 2–5 g/L with a wetting agent, at lights-off or low light; new leaves green faster. Grower practice. Do not spray flowers.
  • Soil: dolomitic lime if the soil is also acidic (slow); Epsom salt dissolved in irrigation water for a quick response.
  • Rebalance K: if K is above about 300 mg/L, bring it down instead of adding Mg.

How to confirm it worked

Yellowing stops climbing within a week; new leaves stay fully green. Old interveinal damage stays. Tissue Mg 0.30–0.65% [5].

Common mistakes

  • Adding Epsom salt repeatedly in soil without testing; sulfate and EC build up.
  • Missing the real cause (K excess or low pH).
  • Confusing Mg (old leaves) with Fe/Mn (new leaves).

Evidence

  • Mg deficiency symptoms on older leaves: Established [3][4].
  • Veg optimum 35–70 mg/L: Supported (one cultivar, one lab [1]).
  • Mg increases cannabinoid/terpene production: Supported (one study [2]).
  • Foliar Mg as a quick fix: Grower practice, consistent with other crops.
  • "LEDs need more Cal-Mag": Myth (GenetixBay house position); Mg demand tracks cultivar, water, medium and pH [6].

Questions this article answers

Why are my lower leaves yellow between the veins?

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

How much magnesium does cannabis need?

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

Can I use Epsom salt on cannabis? How much?

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

Is it magnesium deficiency or too much potassium?

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

Does magnesium increase THC or terpenes?

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

Do LED lights need more magnesium?

Magnesium sits at the centre of chlorophyll. Cannabis trials put the optimum at about 35–70 mg/L Mg in veg, and Mg supply raised cannabinoid and terpene production in flower. Deficiency shows as interveinal yellowing on older leaves with green veins; it is often induced by low pH or by too much potassium or calcium rather than an actual lack of Mg.

Sources

  1. Morad D, Bernstein N. 2023. Response of medical cannabis to magnesium (Mg) supply at the vegetative growth phase. Plants 12(14):2676. doi.org/10.3390/plants12142676
  2. Morad D, Bernstein N. 2025. From deficiency to toxicity: magnesium increases cannabinoid and terpene production in cannabis plants. PMC12739851. pmc.ncbi.nlm.nih.gov/articles/PMC12739851/
  3. Cockson P, et al. 2019. Applied Sciences 9(20):4432. doi.org/10.3390/app9204432
  4. Llewellyn D, et al. 2023. Plants 12(3):422. doi.org/10.3390/plants12030422
  5. Suchoff D, et al. 2026. NC State Extension AG-904. content.ces.ncsu.edu/hemp-leaf-tissue-nutrient-ranges
  6. Saloner A, Sacks MM, Bernstein N. 2019. Frontiers in Plant Science 10:1369. doi.org/10.3389/fpls.2019.01369
  7. Marschner P (ed.). 2012. Marschner's Mineral Nutrition of Higher Plants, 3rd ed. doi.org/10.1016/C2009-0-63043-9

Was this helpful?

Tell us by joining the waitlist: Founding Members shape what the Professor writes next.

Professor Greenleaf

Grow with the Professor.

The GenetixBay community is coming: honest grow journals, permanent GB-IDs for genetics, and a Professor who answers with citations. Founding Members get first access and the lowest numbers in the archive.